Search on: CASEIN KINASES 
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Descriptor English:   Casein Kinases 
Descriptor Spanish:   Caseína Quinasas 
Descriptor Portuguese:   Caseína Quinases 
Synonyms English:   Kinase, Casein
Kinases, Casein
Casein Kinase  
Tree Number:   D08.811.913.696.620.682.700.140
D12.776.476.150
Definition English:   A group of protein-serine-threonine kinases that was originally identified as being responsible for the PHOSPHORYLATION of CASEINS. They are ubiquitous enzymes that have a preference for acidic proteins. Casein kinases play a role in SIGNAL TRANSDUCTION by phosphorylating a variety of regulatory cytoplasmic and regulatory nuclear proteins. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   2005(1974) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38707 
Unique Identifier:   D047388 

Occurrence in VHL:
 

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